Stanley B. Prusiner(1942)
MedicineStanley Ben Prusiner is an American neurologist and biochemist. He is the director of the Institute for Neurodegenerative Diseases at the University of California, San Francisco (UCSF). Prusiner discovered prions, a class of infectious self-reproducing pathogens primarily or solely composed of protein, a scientific theory considered by many as a heretical idea when first proposed.
United States
5
Major Awards
8
Publications
74
Citations
4
h-index
N/A
i10-index
9.3
Avg Citations/Paper
Awards & Recognition
Most Cited Works
Top publications by citation count#1
Correction for Prusiner et al., Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
Proceedings of the National Academy of Sciences of the United States of America(2024)
0
citations
#2
Cryo‐EM structure of a novel α‐synuclein filament subtype from multiple system atrophy
FEBS Letters(2024)
7
citations
#3
Expanding the Prion Paradigm to Include Alzheimer and Parkinson Diseases.
JAMA Neurology(2024)
13
citations
#4
1
citations
#5
Correction to Supporting Information for Woerman et al., Familial Parkinson’s point mutation abolishes multiple system atrophy prion replication
Proceedings of the National Academy of Sciences of the United States of America(2024)
0
citations
#6
Severe neurodegeneration in brains of transgenic rats producing human tau prions
Acta Neuropathologica(2024)
5
citations
#7
Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains
Journal of Pharmacology and Experimental Therapeutics(2015)
48
citations
Recent Publications
View all worksCorrection for Prusiner et al., Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
Proceedings of the National Academy of Sciences of the United States of America2024
0citations
Open AccessCryo‐EM structure of a novel α‐synuclein filament subtype from multiple system atrophy
FEBS Letters2024
7citations
Open Access13citations
1citations
Correction to Supporting Information for Woerman et al., Familial Parkinson’s point mutation abolishes multiple system atrophy prion replication
Proceedings of the National Academy of Sciences of the United States of America2024
0citations
Open AccessSevere neurodegeneration in brains of transgenic rats producing human tau prions
Acta Neuropathologica2024
5citations
Open AccessDifferent 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains
Journal of Pharmacology and Experimental Therapeutics2015
48citations
Open AccessExternal Profiles
Career Path
Award progression over time
Apex Elite Prestigious
Co-winners
Shared the same award in the same year
Education
Perelman School of Medicine at the University of Pennsylvania(Doctor of Medicine)
University of California, San Francisco
Walnut Hills High School
Career Timeline
University of California, San Francisco?–present
University of California, Berkeley?–present
Academy Memberships
National Academy of Sciences (US)American Academy of Arts and SciencesRoyal Society of Canada
Top Publications
Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components
Neuron2021191 citations
Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer’s disease
Proceedings of the National Academy of Sciences2018129 citations
Aβ and tau prion-like activities decline with longevity in the Alzheimer’s disease human brain
Science Translational Medicine2019124 citations
Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines
Acta Neuropathologica201975 citations
Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy
Proceedings of the National Academy of Sciences202275 citations
Books
Related Laureates
Other winners of the same award(s)

Shinya Yamanaka
Breakthrough Prize in Life Sciences (2013)

Sydney Brenner
Dan David Prize (2003)

Paul Berg
Gairdner International Award (1983)

Katalin Karikó
Gruber Prize in Neuroscience (2024)

Drew Weissman
Nobel Prize in Physiology or Medicine (2023)
FZ
Feng Zhang
Gruber Prize in Genetics (2022)

Huda Zoghbi
Horwitz Prize (2022)

David Julius
Nobel Prize in Physiology or Medicine (2021)
Data Sources
Profile data aggregated from Semantic Scholar, Wikidata, ORCID, and curated award records. Citation metrics may vary between sources.


