Barry Sharpless(1941)
ArtsKarl Barry Sharpless is an American stereochemist. He is a two-time Nobel laureate in chemistry, known for his work on stereoselective reactions and click chemistry.
United StatesScripps Research Institute
2
Major Awards
743
Publications
107,978
Citations
136
h-index
408
i10-index
145.3
Avg Citations/Paper
Awards & Recognition
Career History
Professor
Scripps Research
La Jolla, US
Education
Stanford University
Ph.D.
Organic Chemistry
1968
Dartmouth College
B.A.
1963
Research Funding
NEW ASYMMETRIC PROCESSES FOR USE IN ORGANIC SYNTHESIS
National Institute of General Medical Sciences
New Metal Catalyzed Organic Transformations
Directorate for Mathematical & Physical Sciences
The Reactivity of Metal-Oxo and Metal-Imido Groups
Directorate for Mathematical & Physical Sciences
Drug Design Cycle targeting HIV Protease Drug Resistance
National Institute of General Medical Sciences
Practical Organic Oxidations in Water (TSE 99-A)
Directorate for Mathematical & Physical Sciences
Sulfur(VI) Fluoride Exchange (SuFEx) Click Chemistry in Macromolecule Synthesis and Fabrication
Directorate for Mathematical & Physical Sciences
External Profiles
Career Path
Award progression over time
Apex Elite Prestigious
Education
Friends' Central School(high school diploma)
Stanford University(Doctor of Philosophy)
Dartmouth College(bachelor's degree)
Dartmouth College(Bachelor of Arts)
Harvard University
Doctoral Advisor
Eugene van Tamelen
Career Timeline
Massachusetts Institute of Technology?–present
Stanford University?–present
Scripps Research1990–present
Top Publications
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF<sub>4</sub>)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins
Angewandte Chemie International Edition2019158 citations
SuFExable polymers with helical structures derived from thionyl tetrafluoride
Nature Chemistry2021150 citations
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery
Nature Chemistry2020130 citations
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
Angewandte Chemie International Edition2020123 citations
Sulfur fluoride exchange
Nature Reviews Methods Primers202396 citations
Related Laureates
Other winners of the same award(s)
CR
Carolyn R. Bertozzi
Priestley Medal (2023)
AH
Ahmed H. Zewail
Davy Medal (2011)
HC
Herbert C. Brown
Wolf Prize in Chemistry (1981)
Omar Yaghi
Nobel Prize in Chemistry (2025)
Paul Alivisatos
Kyoto Prize in Basic Sciences (2022)
David MacMillan
Wolf Prize in Chemistry (2021)
JoAnne Stubbe
Priestley Medal (2020)
Geraldine Richmond
Priestley Medal (2018)
Data Sources
Profile data aggregated from OpenAlex, Wikidata, ORCID, and curated award records. Citation metrics may vary between sources.